Guillain-Barré syndrome

被引:0
作者
Urban P.P. [1 ]
Nix W.A. [1 ]
机构
[1] Klinik und Poliklinik für Neurologie, Johannes Gutenberg Universität Mainz, 55101 Mainz
来源
Notfall & Rettungsmedizin | 2005年 / 8卷 / 4期
关键词
Guillain-Barré-Syndrom; Immunoglobulins; Miller-Fisher-syndrome; Plasmapheresis;
D O I
10.1007/s10049-005-0739-1
中图分类号
学科分类号
摘要
The Guillain-Barré syndrome (GBS) is an acute, immune-mediated polyneuropathy with progressive flaccid limb weakness which evolves more or less symmetrically over a period of several days also affecting the sensory nerves in most cases. Frequently, the cranial nerves, the respiratory muscles, and the autonomic system are also affected. Most often, GBS occurs after a preceding bacterial or viral illness and the immune-mediated demyelination preferentially affects the nerve roots and distal nerve terminals. Equal effective and causal treatment options are plasmapheresis and high-dose immunoglobulins. Steroids show no benefit. The prognosis is also improved by an effective symptomatic treatment including mechanical ventilation or treatment of the autonomic dysfunction. © Springer Medizin Verlag 2005.
引用
收藏
页码:281 / 285
页数:4
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