Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi's sarcoma presenting as acute intestinal obstruction: A case report

被引：5

作者：

Pal J. ^{[1
]}

Shrivastav A. ^{[1
]}

Pathak H. ^{[2
]}

Sarkar D. ^{[3
]}

机构：

[1] Department of Medicine, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal

[2] Department of Medicine, KPC Medical College and Hospital, Kolkata

[3] Department of Surgery, Institute of Postgraduate Medical Education and Research, Kolkata

来源：

Journal of Medical Case Reports | / 5卷 / 1期

关键词：

Herpes Zoster; Immune Reconstitution Inflammatory Syndrome; Gastrointestinal Involvement; Acute Intestinal Obstruction; Advanced Human Immunodeficiency Virus Disease;

D O I：

10.1186/1752-1947-5-327

中图分类号：

学科分类号：

摘要：

Introduction. Immune reconstitution inflammatory syndrome during anti-retroviral treatment of acquired immunodeficiency syndrome (AIDS) -associated gastrointestinal Kaposi's sarcoma has rarely been reported. Case Presentation. A 36-year-old Asian Indian male, newly diagnosed with AIDS and treatment nave, was started on highly active antiretroviral therapy (HAART). He developed acute intestinal obstruction after four weeks of therapy. A laparotomy was done with excision and adhesiolysis leading to relief of symptoms. A histology report revealed the lesion to be Kaposi's sarcoma. Our patient was diagnosed to be having immune reconstitution inflammatory syndrome associated with AIDS-associated gastrointestinal limited Kaposi's sarcoma, which presented as acute intestinal obstruction. Our patient was treated with paclitaxel post-operatively and HAART was continued. Our patient responded to therapy. Conclusion: Immune reconstitution inflammatory syndrome involving Kaposi's sarcoma may occur in HAART-nave individuals with AIDS-related Kaposi's sarcoma. Gastrointestinal Kaposi's sarcoma may present with sudden increase in size or inflammation leading to acute intestinal obstruction. This does not indicate failure of HAART or a need for changes in anti-retroviral regimen. © 2011 Pal et al; licensee BioMed Central Ltd.

引用

共 9 条

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