Simultaneous symptomatic Rathke's cleft cyst and GH secreting pituitary adenoma: A case report

被引:21
作者
Bader L.J. [1 ]
Carter K.D. [1 ]
Latchaw R.E. [2 ]
Ellis W.G. [4 ]
Wexler J.A. [3 ]
Watson J.C. [1 ,5 ]
机构
[1] Department of Neurological Surgery, UC Davis Medical Center, Sacramento, CA
[2] Department of Neuroradiology, UC Davis Medical Center, Sacramento, CA
[3] Department of Endocrinology, UC Davis Medical Center, Sacramento, CA
[4] Department of Neuropathology, UC Davis Medical Center, Sacramento, CA
[5] Jacobi Medical Center, Bronx, NY 10804
关键词
Acromegaly; Extended transsphenoidal approach; GH-secreting adenoma; Pituitary adenoma; Rathke's cleft cyst; Surprasellar cyst;
D O I
10.1023/B:PITU.0000044632.15978.44
中图分类号
学科分类号
摘要
A case of symptomatic Rathke's cleft cyst and growth hormone (GH) secreting pituitary adenoma is described. A patient presented with a visual field deficit and a brain magnetic resonance imaging (MRI) study demonstrated compression of the optic chiasm by a large suprasellar cyst and a small lesion in the sellar consistent with a microadenoma. Preoperative clinical evaluation revealed mild acromegalic features, glucose intolerance, hypertension, hypercholesterolemia, and carpel tunnel syndrome, and blood testing confirmed an elevated insulin-like growth factor-1 (IGF-1). A modified transsphenoidal skull based approach was performed for selective transsphenoidal adenomectomy and decompression of the surprasellar cyst. The patient had an uneventful postoperative course with resolution of the visual field deficits and dysmenorrhea. Endocrine testing at two-month post procedure were normal. While there have been a small number of cases reported of concomitant pituitary adenomas and Rathke's cleft cysts, there is no report known to these authors of coexisting symptomatic lesions. © 2004 Kluwer Academic Publishers.
引用
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页码:39 / 44
页数:5
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