Social support and resilience to stress across the life span: A neurobiologic framework

被引：206
作者：
Ozbay F. [1 ]
Fitterling H. [1 ]
Charney D. [1 ]
Southwick S. [1 ]
机构：
[1] Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, One Gustave L. Levy Place
来源：
Current Psychiatry Reports | 2008年 / 10卷 / 4期
关键词：
Social Support; Oxytocin; DHEA; Active Coping; Biol Psychiatry;
D O I：
10.1007/s11920-008-0049-7
中图分类号：
学科分类号：
摘要：
This review discusses selected neurobiologic and genetic factors - including noradrenergic and hypothalamic-pituitary-adrenal axis markers, oxytocin, pathways, and serotonin transporter and brain-derived neurotrophic factor gene polymorphisms - in the context of resilience to stress, with an emphasis on social support. Social support's impact on medical and psychiatric health outcomes is reviewed, and putative mediators are discussed. The reviewed literature indicates that social support is exceptionally important to maintaining good physical and psychological health in the presence of genetic, developmental, and other environmental risks. Future studies should continue to explore the neurobiologic factors associated with social support's contribution to stress resilience. Copyright © 2008 by Current Medicine Group LLC.
引用
收藏
页码：304 / 310
页数：6
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