Trends in analytical atomic and molecular mass spectrometry in biology and the life sciences

被引：0
作者：
Maria Careri
Alessandro Mangia
机构：
[1] Università degli Studi di Parma,Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica Fisica
来源：
Analytical and Bioanalytical Chemistry | 2011年 / 399卷
关键词：
Mass spectrometry imaging; Ion mobility mass spectrometry; Laser ablation; ICP–MS; Matrix-free laser desorption/ionization MS; Microfluidics; Miniature mass spectrometers; Multiplexed analysis; Biosciences;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Trends in analytical atomic and molecular mass spectrometry (MS) are reviewed here with an emphasis on problems related to biology and the life sciences. The move towards novel desorption/ionization techniques including matrix-free laser desorption-ionization MS and recent technological developments in MS imaging of elements, small molecules, and proteins are discussed. Recent developments in the interfacing of microfluidics with MS are also reviewed. Metabolic profiling, evaluation of biomarkers, pharmaceutical metabolite identification, and many related topics are addressed.
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页码：2585 / 2595
页数：10
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