Beta-lapachone inhibits proliferation and induces apoptosis in retinoblastoma cell lines

[21] De Potter P(1998)Inhibition of poly(ADP-ribose) polymerase activation attenuates beta-lapachone-induced necrotic cell death in human osteosarcoma cells Free Radic Biol Med 24 660-670

[22] Levy C(1997)Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response Int J Cancer 73 707-714

[23] Doz F(1998)Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells Cancer Res 58 1876-1885

[24] Quintana E(2003)Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone Proc Natl Acad Sci USA 100 2674-2678

[25] Pacquement H(1993)Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone J Biol Chem 268 22463-22468

[26] Michon J(1997)Selective killing of cancer cells by beta-lapachone: direct checkpoint activation as a strategy against cancer Cancer Res 57 620-627

[27] Schlienger P(2000)Beta-lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin J Biol Chem 275 5416-5424

[28] Friedman DL(1995)Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones Oncol Res 7 289-297

[29] Himelstein B(2002)NAD(P)H: quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity Exp Hematol 30 711-720

[30] Shields CL(2002)Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line Nat Cell Biol 4 859-864

[21] De Potter P(1998)Inhibition of poly(ADP-ribose) polymerase activation attenuates beta-lapachone-induced necrotic cell death in human osteosarcoma cells Free Radic Biol Med 24 660-670

[22] Levy C(1997)Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response Int J Cancer 73 707-714

[23] Doz F(1998)Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells Cancer Res 58 1876-1885

[24] Quintana E(2003)Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone Proc Natl Acad Sci USA 100 2674-2678

[25] Pacquement H(1993)Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone J Biol Chem 268 22463-22468

[26] Michon J(1997)Selective killing of cancer cells by beta-lapachone: direct checkpoint activation as a strategy against cancer Cancer Res 57 620-627

[27] Schlienger P(2000)Beta-lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin J Biol Chem 275 5416-5424

[28] Friedman DL(1995)Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones Oncol Res 7 289-297

[29] Himelstein B(2002)NAD(P)H: quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity Exp Hematol 30 711-720

[30] Shields CL(2002)Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line Nat Cell Biol 4 859-864