Role of multidetector CT and FDG-PET/CT in the diagnosis of local and distant recurrence of resected rectal cancer

被引：40
作者：
Bellomi M. [1 ,2 ]
Rizzo S. [2 ]
Travaini L.L. [3 ]
Bazzi L. [1 ]
Trifirò G. [3 ]
Zampino M.G. [4 ]
Radice D. [5 ]
Paganelli G. [3 ]
机构：
[1] Facoltà di Medicina e Chirurgia, Università degli Studi di Milano, I-20122 Milano
[2] Divisione di Radiologia, Istituto Europeo di Oncologia IRCCS, I-20141, Milano
[3] Divisione di Medicina Nucleare, Istituto Europeo di Oncologia IRCCS, I-20141, Milano
[4] Divisione di Oncologia Medica, Istituto Europeo di Oncologia IRCCS, I-20141, Milano
[5] Divisione di Epidemiologia e Biostatistica, Istituto Europeo di Oncologia IRCCS, I-20141, Milano, Via Ripamonti
来源：
La radiologia medica | 2007年 / 112卷 / 5期
关键词：
Computed tomography; Fluorodeoxyglucose; PET/CT; Rectal cancer; Recurrence;
D O I：
10.1007/s11547-007-0172-2
中图分类号：
学科分类号：
摘要：
Purpose. The aim of this study was to compare the diagnostic value of multidetector computed tomography (MDCT) and F18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT) for the detection of local and distant recurrence in patients operated on for rectal cancer. Materials and methods. Sixty-seven patients who underwent radical surgery for rectal cancer and were followed up with FDG-PET/CT and MDCT were included in this retrospective study. The FDG-PET/CT and MDCT findings were independently compared with histological sampling or 2 years' follow-up. Results. Local recurrence occurred in 15/67 patients. MDCT diagnosed local recurrence in 15/15 cases and FDG-PET/CT in 14/15. Sensitivity and specificity were 100% and 98% for MDCT and 93% and 98% for FDG-PET/CT, respectively. Hepatic lesions were found in 17/67 patients. All hepatic metastases were detected by both techniques. Pulmonary metastases occurred in 8/67 patients: they were correctly identified in all cases by MDCT and in 6/8 by FDG-PET/CT. Conclusions. MDCT and FDG-PET/CT showed high sensitivity and specificity for the detection of local recurrence of rectal cancer. Both techniques were equally accurate for the detection of hepatic metastases. MDCT showed slightly higher sensitivity and positive predictive value in detecting pulmonary metastases compared with FDG-PET/CT. © 2007 Springer-Verlag.
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页码：681 / 690
页数：9
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