Normal levels of serum IGF-I: determinants and validity of current reference ranges

被引：0
作者：
G. Brabant
H. Wallaschofski
机构：
[1] Christie Hospital,Department of Endocrinology
[2] University of Greifswald,Department of Gastroenterology, Endocrinology and Nutrition
来源：
Pituitary | 2007年 / 10卷
关键词：
IGF-I; Gender; Age; Genetics; Nutrition; Disease dependency;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Insulin like growth factor I (IGF-I) represents the key marker for the evaluation of Growth hormone (GH) status. As a large number of determinants including age, gender, genetic factors, nutrition, and disease states influence IGF-I serum levels, accurate normative data are essential to translate patient data into diagnostic meaning or even use IGF-I levels for adequate monitoring of patients with an over- or under-active GH axis. Even though reference ranges have been developed in large cohorts of healthy subjects, the dependency of these data on a given assay technology argues for assay specific normative data for IGF-I.
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页码：129 / 133
页数：4
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