Autoantibodies and Their Role in Scleroderma Clinical Care

被引：0
作者：
Robyn T. Domsic
Thomas A. Medsger
机构：
[1] University of Pittsburgh,
来源：
Current Treatment Options in Rheumatology | 2016年 / 2卷 / 3期
关键词：
Systemic sclerosis; Autoantibodies; Anti-nuclear antibodies;
D O I：
10.1007/s40674-016-0050-y
中图分类号：
学科分类号：
摘要：
The importance of autoantibodies in systemic sclerosis (SSc) diagnosis and prognosis has been increasingly recognized. This review discusses the current knowledge of autoantibodies in systemic sclerosis (SSc) with respect to clinical care. We focus primarily on the SSc-associated serum autoantibodies and their recognized SSc clinical phenotypes or characteristics. Geographic regional differences in autoantibody prevalence are discussed. Potential pitfalls in commercially available autoantibody testing are considered. Finally, contemporary literature in regards to antibodies to functional molecules is reviewed.
引用
收藏
页码：239 / 251
页数：12
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