4-Hydroxy-2-quinolones. 92. Reaction of 1-R-4-chloro-3-ethoxycarbonyl-2- oxo-1,2-dihydroquinolines with anilines

被引：0

作者：

Ukrainets I.V. ^{[1
]}

Sidorenko L.V. ^{[1
]}

Gorokhova O.V. ^{[1
]}

Jaradat N.A. ^{[2
]}

机构：

[1] National Pharmaceutical University

[2] An-Najah National University College of Pharmacy, Nablus

来源：

Chemistry of Heterocyclic Compounds | 2006年 / 42卷 / 3期

关键词：

4-arylamino-2-oxo-1,2-dihydroquinolines; Anti-inflammatory activity; Decarboxylation; X-ray structural analysis;

D O I：

10.1007/s10593-006-0091-5

中图分类号：

学科分类号：

摘要：

A preparative method is proposed and the synthesis of 4-arylamino-2-oxo-1, 2-dihydroquinolines has been effected. An X-ray structural investigation of 4-(4-chlorophenylamino)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxylic acid has been carried out enabling the ease of decarboxylating such compounds to be substantiated. Results are given of a study of the anti-inflammatory activity of the synthesized compounds. ©2006 Springer Science+Business Media, Inc.

引用

页码：343 / 351

页数：8

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