4-Hydroxy-2-quinolones. 92. Reaction of 1-R-4-chloro-3-ethoxycarbonyl-2- oxo-1,2-dihydroquinolines with anilines

被引：0
|
作者：
Ukrainets I.V. [1 ]
Sidorenko L.V. [1 ]
Gorokhova O.V. [1 ]
Jaradat N.A. [2 ]
机构：
[1] National Pharmaceutical University
[2] An-Najah National University College of Pharmacy, Nablus
来源：
Chemistry of Heterocyclic Compounds | 2006年 / 42卷 / 3期
关键词：
4-arylamino-2-oxo-1,2-dihydroquinolines; Anti-inflammatory activity; Decarboxylation; X-ray structural analysis;
D O I：
10.1007/s10593-006-0091-5
中图分类号：
学科分类号：
摘要：
A preparative method is proposed and the synthesis of 4-arylamino-2-oxo-1, 2-dihydroquinolines has been effected. An X-ray structural investigation of 4-(4-chlorophenylamino)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxylic acid has been carried out enabling the ease of decarboxylating such compounds to be substantiated. Results are given of a study of the anti-inflammatory activity of the synthesized compounds. ©2006 Springer Science+Business Media, Inc.
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页码：343 / 351
页数：8
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