ncRNAs regulate bovine adipose tissue deposition

被引:0
作者
Zhaoxiong Lei
Huiguang Wu
Yan Xiong
Dawei Wei
Xingping Wang
Zhuoma Luoreng
Xiaoyan Cai
Yun Ma
机构
[1] Ningxia University,School of Agriculture
[2] Ningxia University,Key Laboratory of Ruminant Molecular and Cellular Breeding
[3] Ningxia Hui Autonomous Region,College of Veterinary Medicine
[4] Yangzhou University,Key Laboratory of Qinghai
[5] Southwest Minzu University,Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education
[6] Xinyang Normal University,College of Life Science
来源
Molecular and Cellular Biochemistry | 2021年 / 476卷
关键词
lncRNA; miRNA; circRNA; Adipose tissue; Adipogenesis; Bovine;
D O I
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中图分类号
学科分类号
摘要
Lipid metabolism, which encompasses synthesis and degradation of lipids, is critical for a wide range of cellular functions, including structural and morphological properties of organelles, energy storage, signalling, and the stability and function of membrane proteins. Adipose tissue is a dynamic tissue type that performs a lot of significant physiological functions, including secretion, and is involved in maintaining homeostasis and in regulatory roles of other tissues based on paracrine or endocrine. More recently, several classes of non-coding RNAs (ncRNAs), such as long non-coding RNA (lncRNA), microRNA (miRNA) and circular RNA (circRNA), have been discovered in adipocytes, and they act as critical regulators of gene expression in adipogenesis and regulate adipogenesis through multiple pathways. In the present paper, we discussed several classes of non-coding RNAs and summarized the latest research on the regulatory role of ncRNAs in bovine adipogenesis. We gave examples for known modes of action to look forward to providing reference information future scientific research in cattle breeding.
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页码:2837 / 2845
页数:8
相关论文
共 369 条
  • [51] Khalid F(2004)A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling Biochem Biophys Res Commun 313 320-326
  • [52] Wagner A(2020)miR-424 promotes bovine adipogenesis through an unconventional post-transcriptional regulation of STK11 Front Genet 11 145-155
  • [53] Johnsson P(2014)Lkb1 is indispensable for skeletal muscle development, regeneration, and satellite cell homeostasis Stem Cells 32 2893-2907
  • [54] Lipovich L(2018)MicroRNA-200a regulates adipocyte differentiation in the domestic yak Bos grunniens Gene 650 41-48
  • [55] Grandér D(2014)MicroRNA-224 impairs adipogenic differentiation of bovine preadipocytes by targeting LPL Mol Cell Probes 44 29-36
  • [56] Morris KV(2020)RNA-seq reveal role of bovine TORC2 in the regulation of adipogenesis Arch Biochem Biophys 680 108236-108247
  • [57] Ulitsky I(2011)Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet Diabetes 60 464-476
  • [58] Bartel DP(2017)Identification of the interaction between bta-miR-370 and OLR1 gene in bovine adipocyte Anim Genet 48 455-458
  • [59] Tajbakhsh S(2005)PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1 J Clin Invest 115 2244-2256
  • [60] Akinobu M(2020)MiR-145 reduces the activity of PI3K/Akt and MAPK signaling pathways and inhibits adipogenesis in bovine preadipocytes Genomics 112 2688-2694