ncRNAs regulate bovine adipose tissue deposition

被引：0
作者：
Zhaoxiong Lei
Huiguang Wu
Yan Xiong
Dawei Wei
Xingping Wang
Zhuoma Luoreng
Xiaoyan Cai
Yun Ma
机构：
[1] Ningxia University,School of Agriculture
[2] Ningxia University,Key Laboratory of Ruminant Molecular and Cellular Breeding
[3] Ningxia Hui Autonomous Region,College of Veterinary Medicine
[4] Yangzhou University,Key Laboratory of Qinghai
[5] Southwest Minzu University,Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education
[6] Xinyang Normal University,College of Life Science
来源：
Molecular and Cellular Biochemistry | 2021年 / 476卷
关键词：
lncRNA; miRNA; circRNA; Adipose tissue; Adipogenesis; Bovine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Lipid metabolism, which encompasses synthesis and degradation of lipids, is critical for a wide range of cellular functions, including structural and morphological properties of organelles, energy storage, signalling, and the stability and function of membrane proteins. Adipose tissue is a dynamic tissue type that performs a lot of significant physiological functions, including secretion, and is involved in maintaining homeostasis and in regulatory roles of other tissues based on paracrine or endocrine. More recently, several classes of non-coding RNAs (ncRNAs), such as long non-coding RNA (lncRNA), microRNA (miRNA) and circular RNA (circRNA), have been discovered in adipocytes, and they act as critical regulators of gene expression in adipogenesis and regulate adipogenesis through multiple pathways. In the present paper, we discussed several classes of non-coding RNAs and summarized the latest research on the regulatory role of ncRNAs in bovine adipogenesis. We gave examples for known modes of action to look forward to providing reference information future scientific research in cattle breeding.
引用
收藏
页码：2837 / 2845
页数：8
相关论文
共 369 条
  • [1] Albrecht E(2011)Cellular conditions for intramuscular fat deposition in Japanese Black and Holstein steers Meat Sci 89 13-20
  • [2] Gotoh T(1998)Understanding adipocyte differentiation Physiol Rev 78 783-809
  • [3] Ebara F(1996)Rumen development in the calf Br J Nutr 20 171-188
  • [4] Gregoire F(2020)Association between rumen microbiota and marbling score in Korean native beef cattle Animals 10 712-725
  • [5] Smas CM(2017)LncRNA Gm15290 sponges miR-27b to promote PPARγ-induced fat deposition and contribute to body weight gain in mice Biochim Biophys Acta 493 1168-1175
  • [6] Sul HS(2019)A novel lnc-RNA, named lnc-ORA, is identified by RNA-seq analysis, and its knockdown inhibits adipogenesis by regulating the PI3K/AKT/mTOR signaling pathway Cells 8 477-499
  • [7] Stobo IJF(2019)LncRNA IMFNCR promotes intramuscular adipocyte differentiation by sponging miR-128-3p and miR-27b-3p Front Genet 10 42-61
  • [8] Roy JHB(2019)The effect of microRNA-331-3p on preadipocytes proliferation and differentiation and fatty acid accumulation in laiwu pigs Biomed Res Int 2019 9287804-9287817
  • [9] Gaston HJ(2018)RNA-mediated gene regulation is less evolvable than transcriptional regulation Proc Natl Acad Sci U S A 115 E3481-E3490
  • [10] Kim M(2014)Evolutionary conservation of long non-coding RNAs; sequence, structure, function Biochimica et Biophysica Acta-Biomembranes 1840 1063-1071
12345678910