Role of lipoprotein-associated phospholipase A2 in atherosclerosis

被引:0
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作者
Shahar Lavi
Joerg Herrmann
Ronit Lavi
Joseph P. McConnell
Lilach O. Lerman
Amir Lerman
机构
[1] Mayo Clinic,Division of Cardiovascular Diseases
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关键词
Acute Coronary Syndrome; Stable Coronary Artery Disease; Arterioscler Thromb Vasc Biol; Coronary Endothelial Dysfunction; Stable Coronary Disease;
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摘要
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a biomarker that can be used to assess the risk for cardiovascular disease and events. In addition to being a useful marker of a risk factor, several studies suggest that Lp-PLA2 has a pathophysiologic role in the atherosclerotic disease process. In this article, we review this aspect and its therapeutic implications.
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