Life-threatening infection due to community-acquired methicillin-resistant Staphylococcus aureus: case report and review

被引：0
作者：
Kalomoira Kefala-Agoropoulou
Efthimia Protonotariou
Danai Vitti
Sofia Sarafidou
Athanasia Anastasiou
Konstantinos Kollios
Emmanuel Roilides
机构：
[1] Hippokration Hospital,3rd Department of Pediatrics, Aristotle University School of Medicine
[2] Hippokration Hospital,Microbiology Department
[3] Hippokration Hospital,Radiology Department
来源：
European Journal of Pediatrics | 2010年 / 169卷
关键词：
CA-MRSA infection; Children; Treatment; A gene; PVL gene;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We report an unusual case of serious, multifocal, invasive infection due to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in a 10-year-old girl with favorable outcome. The child manifested femoral osteomyelitis, pyomyositis, deep femoral vein thrombosis, pneumonia, encephalopathy, and disturbances of almost all organs. She remained in a critical condition for a week. Fever persisted for 6 weeks and acute phase reactants remained increased for 6 months, necessitating a 7-month antistaphylococcal therapy with a glycopeptide and clindamycin. This led to resolution of infection-associated problems during the subsequent 36 months of follow-up. CA-MRSA strain isolated from the patient harbored both staphylococcal chromosomal cassette type IV (SCCmec type IV) and Panton–Valentine leukocidin genes. A literature review of serious CA-MRSA infections indicated that only a small minority of published cases had favorable outcome.
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页码：47 / 53
页数：6
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