New Imaging Techniques for Atherosclerotic Plaque Characterization

被引：0

作者：

Lavra F. ^{[1
,2
]}

De Cecco C.N. ^{[1
]}

Varga-Szemes A. ^{[1
]}

De Santis D. ^{[1
,3
]}

Albrecht M.H. ^{[1
,4
]}

Lesslie V.W. ^{[1
]}

van Assen M. ^{[1
,5
]}

von Knebel Doeberitz P. ^{[1
]}

Mastrodicasa D. ^{[1
,6
]}

Eid M. ^{[1
]}

Apfaltrer G. ^{[1
,7
]}

Stalcup S. ^{[8
]}

Bayer R.R. ^{[1
,9
]}

Saba L. ^{[2
]}

Joseph Schoepf U. ^{[1
]}

机构：

[1] Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC

[2] Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), Cagliari

[3] Department of Radiological Sciences, Oncological and Pathological Sciences, University of Rome Sapienza, Latina

[4] Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt

[5] Center for Medical Imaging, University Medical Center Groningen, North East Netherlands, Groningen

[6] Section of Diagnostic Imaging and Therapy – Radiology Division, Department of Neuroscience, Imaging and Clinical Science, “G. d’Annunzio” University, Chieti

[7] Division of Pediatric Radiology, Department of Radiology, Medical University of Graz, Graz

[8] Department of Radiology, Medical University of South Carolina, Charleston, SC

[9] Division of Cardiology, Medical University of South Carolina, Charleston, SC

来源：

Current Radiology Reports | / 5卷 / 11期

关键词：

Atherosclerosis; Computed tomography; Intravascular ultrasound; Magnetic resonance imaging; Plaque characterization; Vulnerable plaque;

D O I：

10.1007/s40134-017-0252-6

中图分类号：

学科分类号：

摘要：

Purpose: Previously, the imaging of atherosclerotic plaque has been limited to the assessment of vessel stenosis and occlusion. However, recent technological advances have allowed for more detailed plaque characterization. This article will address recent advancements in plaque characterization using both invasive and noninvasive techniques, as well as potential improvements in patient evaluation and targeted therapies. Recent Findings: Recent findings have demonstrated that plaque composition affects plaque vulnerability, or the propensity of a plaque to rupture and cause acute thrombus formation with potentially life-threatening downstream implications. Summary: Newly introduced invasive and noninvasive techniques allow for a comprehensive assessment of atherosclerotic plaque to classify high-risk patients requiring more intensive therapy. © 2017, Springer Science+Business Media, LLC.

引用

共 81 条

[1]

Hansson G.K., Libby P., Tabas I., Inflammation and plaque vulnerability, J Intern Med, 278, 5, pp. 483-493, (2015)

[2]

Libby P., Tabas I., Fredman G., Fisher E.A., Inflammation and its resolution as determinants of acute coronary syndromes, Circ Res, 114, 12, pp. 1867-1879, (2014)

[3]

Falk E., Nakano M., Bentzon J.F., Finn A.V., Virmani R., Update on acute coronary syndromes: the pathologists’ view, Eur Heart J, 34, 10, pp. 719-728, (2013)

[4]

Freilinger T.M., Schindler A., Schmidt C., Grimm J., Cyran C., Schwarz F., Et al., Prevalence of nonstenosing, complicated atherosclerotic plaques in cryptogenic stroke, JACC Cardiovasc Imaging, 5, 4, pp. 397-405, (2012)

[5]

Gupta A., Gialdini G., Lerario M.P., Baradaran H., Giambrone A., Navi B.B., Et al., Magnetic resonance angiography detection of abnormal carotid artery plaque in patients with cryptogenic stroke, J Am Heart Assoc, 4, 6, (2015)

[6]

Ota H., Magalhaes M.A., Torguson R., Negi S., Kollmer M.R., Spad M.A., Et al., The influence of lipid-containing plaque composition assessed by near-infrared spectroscopy on coronary lesion remodelling, Eur Heart J Cardiovasc Imaging, 17, 7, pp. 821-831, (2016)

[7]

Motoyama S., Ito H., Sarai M., Kondo T., Kawai H., Nagahara Y., Et al., Plaque characterization by coronary computed tomography angiography and the likelihood of acute coronary events in mid-term follow-up, J Am Coll Cardiol, 66, 4, pp. 337-346, (2015)

[8]

Puchner S.B., Liu T., Mayrhofer T., Truong Q.A., Lee H., Fleg J.L., Et al., High-risk plaque detected on coronary CT angiography predicts acute coronary syndromes independent of significant stenosis in acute chest pain: results from the ROMICAT-II trial, J Am Coll Cardiol, 64, 7, pp. 684-692, (2014)

[9]

Dweck M.R., Aikawa E., Newby D.E., Tarkin J.M., Rudd J.H., Narula J., Et al., Noninvasive molecular imaging of disease activity in atherosclerosis, Circ Res, 119, 2, pp. 330-340, (2016)

[10]

Batty J.A., Subba S., Luke P., Gigi L.W., Sinclair H., Kunadian V., Intracoronary imaging in the detection of vulnerable plaques, Curr Cardiol Rep, 18, 3, (2016)

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