Outbreak of Shiga toxin-producing Escherichia-coli-associated hemolytic uremic syndrome in Istanbul in 2015: outcome and experience with eculizumab

被引：0

作者：

Ayşe Ağbaş

Nilüfer Göknar

Nurver Akıncı

Zeynep Yürük Yıldırım

Mehmet Taşdemir

Meryem Benzer

İbrahim Gökçe

Cengiz Candan

Nuran Küçük

Selçuk Uzuner

Gül Özçelik

Demet Demirkol

Lale Sever

Salim Çalışkan

机构：

[1] Istanbul University,Pediatric Nephrology, Cerrahpaşa Faculty of Medicine

[2] Bezmialem Vakıf University,Pediatric Nephrology

[3] Şişli Hamidiye Etfal Education and Research Hospital,Pediatric Nephrology

[4] Istanbul University,Pediatric Nephrology, Istanbul Faculty of Medicine

[5] Koç University,Pediatric Nephrology, Faculty of Medicine

[6] Bakırköy Dr Sadi Konuk Education and Research Hospital,Pediatric Nephrology

[7] Marmara University,Pediatric Nephrology, Faculty of Medicine

[8] Medeniyet University,Pediatric Nephrology, Faculty of Medicine

[9] Kartal Education and Research Hospital,Pediatric Nephrology

[10] Bezmialem Vakıf University,Pediatric Intensive Care Unit, Faculty of Medicine

[11] Koç University,Pediatric Intensive Care Unit, Faculty of Medicine

[12] Istanbul University,Pediatric Intensive Care Unit, Istanbul Faculty of Medicine

来源：

Pediatric Nephrology | 2018年 / 33卷

关键词：

Hemolytic uremic syndrome; HUS; Shiga toxin; STEC; Children; Eculizumab;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：2371 / 2381

页数：10

共 392 条

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[4] Hauswaldt S(2016)An international consensus approach to the management of atypical hemolytic uremic syndrome in children Pediatr Nephrol 31 15-39
[5] Nitschke M(2013)Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome N Engl J Med 368 2169-2181
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[7] Solbach W(1977)Breakdown products of C3 and factor B in hemolytic-uremic syndrome J Lab Clin Med 89 845-850
[8] Knobloch JK(1980)The complement system in hemolytic-uremic syndrome in childhood Clin Nephrol 13 168-171
[9] Frank C(2009)Alternative pathway of complement in children with diarrhea-associated hemolytic uremic syndrome Clin J Am Soc Nephrol 4 1920-1924
[10] Werber D(2009)Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome J Immunol 182 6394-6400