Processing, Distribution, and Function of VGF, a Neuronal and Endocrine Peptide Precursor

被引：0
作者：
Andrea Levi
Gian-Luca Ferri
Elizabeth Watson
Roberta Possenti
Stephen R. J. Salton
机构：
[1] University of Tor Vergata,Department of Neuroscience
[2] University of Cagliari at Monserrato,Neuro
[3] Mount Sinai School of Medicine,&
[4] National Research Council,Endocrine Research, Department of Cytomorphology
来源：
Cellular and Molecular Neurobiology | 2004年 / 24卷
关键词：
VGF; neurotrophin; PC12; endocrine; feeding; metabolism; NGF; BDNF;
D O I：
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中图分类号：
学科分类号：
摘要：
1. The vgf gene encodes a neuropeptide precursor with a restricted pattern of expression that is limited to a subset of neurons in the central and peripheral nervous systems and to specific populations of endocrine cells in the adenohypophysis, adrenal medulla, gastrointestinal tract, and pancreas. In responsive neurons, vgf transcription is upregulated by neurotrophins, the basis for the original identification of VGF as nerve growth factor- (NGF) inducible in PC12 cells (A. Levi, J. D. Eldridge, and B. M. Paterson, Science229:393–395, 1985).
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页码：517 / 533
页数：16
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