High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer’s Disease Via a Specific Tau Phosphorylation Pattern

被引：0
|
作者：
Y. Ito
Shuko Takeda
T. Nakajima
A. Oyama
H. Takeshita
K. Miki
Y. Takami
Y. Takeya
M. Shimamura
H. Rakugi
Ryuichi Morishita
机构：
[1] Osaka University,Department of Clinical Gene Therapy, Graduate School of Medicine
[2] Osaka Psychiatric Medical Center,Osaka Psychiatric Research Center
[3] Osaka University,Department of Geriatric and General Medicine, Graduate School of Medicine
[4] Osaka University,Department of Clinical Nursing, Division of Health Sciences, Graduate School of Medicine
[5] Osaka University,Department of Neurology, Department of Health Development and Medicine, Graduate School of Medicine
来源：
The Journal of Prevention of Alzheimer's Disease | 2024年 / 11卷
关键词：
Alzheimer’s disease; dementia; diabetes mellitus; tau; post-translational modification;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：138 / 148
页数：10
相关论文
共 50 条
  • [21] Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer's disease
    Sonsalla, Michelle M.
    Babygirija, Reji
    Johnson, Madeline
    Cai, Samuel
    Cole, Mari
    Yeh, Chung-Yang
    Grunow, Isaac
    Liu, Yang
    Vertein, Diana
    Calubag, Mariah F.
    Trautman, Michaela E.
    Green, Cara L.
    Rigby, Michael J.
    Puglielli, Luigi
    Lamming, Dudley W.
    GEROSCIENCE, 2024, : 1569 - 1591
  • [22] Alleviative Effect of Alpha-Lipoic Acid on Cognitive Impairment in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats
    Ko, Chih-Yuan
    Xu, Jian-Hua
    Lo, Yangming Martin
    Tu, Rong-Syuan
    Wu, James Swi-Bea
    Huang, Wen-Chung
    Shen, Szu-Chuan
    FRONTIERS IN AGING NEUROSCIENCE, 2021, 13
  • [23] Spirulina platensis alleviates high fat diet-induced cognitive impairment in mice via the gut-brain axis
    Zhou, Tao
    Liu, Yan
    Wang, Qiulian
    Dou, Qingquan
    Li, Xukai
    Pan, Yinping
    Meng, Lingzheng
    Xue, Tian
    JOURNAL OF FUNCTIONAL FOODS, 2021, 86
  • [24] Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer's Disease
    Reilly, Austin M.
    Tsai, Andy P.
    Lin, Peter B.
    Ericsson, Aaron C.
    Oblak, Adrian L.
    Ren, Hongxia
    NUTRIENTS, 2020, 12 (10) : 1 - 18
  • [25] Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer's disease
    Li, Hui-Qin
    Ip, Siu-Po
    Yuan, Qiu-Ju
    Zheng, Guo-Qing
    Tsim, Karl K. W.
    Dong, Tina T. X.
    Lin, Ge
    Han, Yifan
    Liu, Yue
    Xian, Yan-Fang
    Lin, Zhi-Xiu
    BRAIN BEHAVIOR AND IMMUNITY, 2019, 82 : 264 - 278
  • [26] Long-Term High-Fat Diet Consumption Aggravates β-Amyloid Deposition and Tau Pathology Accompanied by Microglial Activation in an Alzheimer's Disease Model
    Liang, Zheng
    Gong, Xiaokang
    Zhao, Yang
    Zhao, Yanna
    Yu, Jing
    Huang, Tiantian
    Yang, Chaoqing
    Wu, Liangwei
    Huang, Mengbing
    Wang, Xiaochuan
    Shu, Xiji
    Bao, Jian
    MOLECULAR NUTRITION & FOOD RESEARCH, 2024, 68 (07)
  • [27] Yeast β-glucan alleviates high-fat diet-induced Alzheimer's disease-like pathologies in rats via the gut-brain axis
    Mo, Xiaoxing
    Cheng, Ruijie
    Shen, Lihui
    Liu, Nian
    Sun, Yunhong
    Lin, Shan
    Jiang, Guanhua
    Li, Xiaoqin
    Peng, Xiaobo
    Zhang, Yan
    Liao, Yuxiao
    Yan, Hong
    Liu, Liegang
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 278
  • [28] High-Fat-Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders
    Lin, Bowen
    Hasegawa, Yu
    Takane, Koki
    Koibuchi, Nobutaka
    Cao, Cheng
    Kim-Mitsuyama, Shokei
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2016, 5 (06):
  • [29] Curcumin Mitigates the High-Fat High-Sugar Diet-Induced Impairment of Spatial Memory, Hepatic Metabolism, and the Alteration of the Gut Microbiome in Alzheimer's Disease-Induced (3xTg-AD) Mice
    Lamichhane, Gopal
    Liu, Jing
    Lee, Su-Jeong
    Lee, Da-Yeon
    Zhang, Guolong
    Kim, Yoo
    NUTRIENTS, 2024, 16 (02)
  • [30] γ-Aminobutyric Acid Attenuates High-Fat Diet-Induced Cerebral Oxidative Impairment via Enhanced Synthesis of Hippocampal Sulfatides
    Si, Xu
    Li, Yibo
    Jiang, Yugang
    Shang, Wenting
    Shui, Guanghou
    Lam, Sin Man
    Blanchard, Chris
    Strappe, Padraig
    Zhou, Zhongkai
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 67 (04) : 1081 - 1091
12345