Evoked potentials in monitoring multiple sclerosis

被引:12
作者
L. Leocani
S. Medaglini
G. Comi
机构
[1] Neurophysiology Department,
[2] Scientific Institute Hospital San Raffaele,undefined
[3] Via Olgettina 60,undefined
[4] I-20132 Milan,undefined
[5] Italy,undefined
关键词
Key words Evoked potentials; Multiple sclerosis; Monitoring;
D O I
10.1007/s100720070032
中图分类号
学科分类号
摘要
The usefulness of evoked potentials (EPs) in the diagnosis of multiple sclerosis is limited by its relatively low sensitivity to subclinical lesions. However, they are still a good tool to assess the integrity of afferent and efferent pathways and to quantify the severity of white matter involvement. Transversal and longitudinal studies have demonstrated good correlation between EP abnormalities and disability, suggesting that multimodal evoked potentials could be useful in monitoring the disease evolution in single patients and as surrogate end points in clinical trials.
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页码:S889 / S891
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