Reciprocal regulation of carbon monoxide metabolism and the circadian clock

被引:0
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作者
Roman Klemz
Silke Reischl
Thomas Wallach
Nicole Witte
Karsten Jürchott
Sabrina Klemz
Veronika Lang
Stephan Lorenzen
Miriam Knauer
Steffi Heidenreich
Min Xu
Jürgen A Ripperger
Michael Schupp
Ralf Stanewsky
Achim Kramer
机构
[1] Laboratory of Chronobiology,Department of Cell and Developmental Biology
[2] Charité Universitätsmedizin Berlin,Division of Biochemistry, Department of Biology
[3] Institute of Pharmacology,undefined
[4] Center for Cardiovascular Research CCR,undefined
[5] Charité Universitätsmedizin Berlin,undefined
[6] Bernhard-Nocht-Institut,undefined
[7] University College London,undefined
[8] University of Fribourg,undefined
[9] Present address: Westfälische Wilhelms-Universität Münster,undefined
[10] Münster,undefined
[11] Germany.,undefined
来源
Nature Structural & Molecular Biology | 2017年 / 24卷
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摘要
Genetic and biochemical assays reveal that carbon monoxide produced by heme catabolism influences circadian rhythm in mammals by altering the activity of transcription factor CLOCK–BMAL1 at clock-gene targets.
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页码:15 / 22
页数:7
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