Mendelian randomisation analysis of clustered causal effects of body mass on cardiometabolic biomarkers

被引:0
作者
Susana Conde
Xiaoguang Xu
Hui Guo
Markus Perola
Teresa Fazia
Luisa Bernardinelli
Carlo Berzuini
机构
[1] Centre for Biostatistics,Department of Brain and Behavioural Sciences
[2] University of Manchester,undefined
[3] National Institute for Health and Welfare (THL),undefined
[4] University of Pavia,undefined
来源
BMC Bioinformatics | / 19卷
关键词
Cardiovascular disease; Causal inference; Egger regression; Metabolomics; Multiple instrumental variables; Weighted median estimator;
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  • [1] Cox DR(2004)Causality: a statistical view Int Stat Rev 72 285-305
  • [2] Wermuth N(1986)Apoupoprotein E isoforms, serum cholesterol, and cancer Lancet 327 507-8
  • [3] Katan MB(2003)Mendelian Randomization: Can Genetic Epidemiology Contribute to Understanding Environmental Determinants of Disease? Int J Epidemiol 32 1-22
  • [4] Davey Smith G(2008)Mendelian randomization: using genes as instruments for making causal inferences in epidemiology Stat Med 27 1133-63
  • [5] Ebrahim S(2017)Insight into rheumatological cause and effect through the use of mendelian randomization Nat Rev Rheumat 13 486-96
  • [6] Lawlor D(2012)Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian Randomisation study Lancet 380 572-80
  • [7] Harbord R(2016)Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator Genet Epidemiol 40 304-14
  • [8] Sterne J(2014)Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change PLoS Med 11 1-17
  • [9] Timpson N(2010)Metabonomic, transcriptomic, and genomic variation of a population cohort Mol Syst Biol 6 502-13
  • [10] Davey Smith G(1990)Identifying independence in Bayesian networks Networks 20 507-34