Synthesis of pyrrolo[2,3-d]pyrimidines with 3-amino-2-hydroxypropyl substituents

被引：0
作者：
L. V. Muzychka
E. V. Verves
I. O. Yaremchuk
O. B. Smolii
机构：
[1] Ukraine National Academy of Sciences,Institute of Bioorganic and Petroleum Chemistry
来源：
Chemistry of Heterocyclic Compounds | 2012年 / 48卷
关键词：
pyrimido[5',4':4,5]pyrrolo[2,1-; ][1,4]oxazines; pyrrolo[2,3-; ]pyrimidines; bromolacto-nization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A novel route has been found for the synthesis of pyrimido[5',4':4,5]pyrrolo[2,1-c][1,4]oxazines. They are promising reagents for the preparation of pyrrolo[2,3-d]pyrimidine-6-carboxylic acid amides which contain a 3-amino-2-hydroxypropyl substituent in position 7 of the heterocyclic ring.
引用
收藏
页码：481 / 487
页数：6
相关论文
共 153 条
[1]  
Mizuno Y(1963)undefined J. Org. Chem. 28 3329-undefined
[2]  
Ikehara M(1963)undefined J. Org. Chem. 28 3331-undefined
[3]  
Watanabe KA(1969)undefined J. Am. Chem. Soc. 91 2102-undefined
[4]  
Suzaki S(1994)undefined J. Org. Chem. 59 6902-undefined
[5]  
Itoh T(1995)undefined J. Med. Chem. 38 3957-undefined
[6]  
Mizuno Y(2004)undefined J. Med. Chem. 47 5284-undefined
[7]  
Ikehara M(1985)undefined J. Med. Chem. 28 1477-undefined
[8]  
Watanabe KA(2006)undefined Bioorg. Med. Chem. Lett. 16 285-undefined
[9]  
Suzaki S(1990)undefined J. Med. Chem. 33 2162-undefined
[10]  
Tolman RL(1996)undefined J. Med. Chem. 39 873-undefined
12345678910