Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage Δ6-desaturase

被引：0
作者：
David Cook
Don Grierson
Craigh Jones
Andrew Wallace
Gill West
Greg Tucker
机构：
[1] The University of Nottingham,School of Biosciences, Division of Nutritional Biochemistry, Loughborough
[2] The University of Nottingham,School of Biosciences, Division of Plant Science, Loughborough
来源：
Molecular Biotechnology | 2002年 / 21卷
关键词：
Tomato; fatty acids; desaturase; nutritional quality; genetic modification;
D O I：
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学科分类号：
摘要：
The improvement of nutritional quality is one potential application for the genetic modification of plants. One possible target for such manipulation is the modification of fatty acid metabolism. In this work, expression of a borage Δ6-desaturase cDNA in tomato (Lycopersicon esculentum L.) has been shown to produce γ-linolenic acid (GLA; 18:3 Δ6,9,12) and octadecatetraenoic acid (OTA; 18:4 Δ6,9,12,15) in transgenic leaf and fruit tissue. This genetic modification has also, unexpectedly, resulted in a reduction in the percentage of linoleic acid (LA 18:2 Δ9,12) and a concomitant increase in the percentage of α-linolenic acid (ALA; 18:3 Δ9,12,15) in fruit tissue. These changes in fatty acid composition are thought to be beneficial for human health.
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页码：123 / 128
页数：5
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