Effect of Highly Mineralized Natural Water on Redox Processes in HaCaT Keratinocytes

被引:0
作者
N. S. Zaitseva
A. V. Chechushkov
P. M. Kozhin
A. E. Lemza
V. O. Tkachev
M. V. Solomatina
V. A. Starostenko
机构
[1] Siberian Division of the Russian Academy of Medical Sciences,Research Center of Clinical and Experimental Medicine
来源
Bulletin of Experimental Biology and Medicine | 2014年 / 156卷
关键词
HaCaT keratinocytes; hyperosmotic stress; oxidative stress; ROS production; transmembrane mitochondrial potential;
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学科分类号
摘要
We studied ROS production by HaCaT keratinocytes, the state of transmembrane mitochondrial potential, and activation of transcription factor Nrf2 in response to brine exposure. It was demonstrated that this exposure induces rapid but moderate decrease in mitochondrial potential, stimulates ROS production, and leads to activation of transcription factor Nrf2.
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页码:810 / 812
页数:2
相关论文
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