Association between radical prostatectomy and risk of herpes zoster

被引：0
作者：
C.-Y. Hsu
P.-R. Chen
H.-J. Chen
J.-A. Liang
机构：
[1] Puli Christian Hospital,Department of Family Medicine
[2] Puli Christian Hospital,Department of Medical Education and Research
[3] National Chi Nan University,Center for General Education
[4] Central Taiwan University of Science and Technology,Department of Optometry
[5] National Taichung University of Science and Technology,Center for General Education
[6] Feng Chia University,Center for General Education
[7] National Chin-Yi University of Technology,Department of General Education
[8] Chaoyang University of Technology,The General Education Center
[9] China Medical University Hospital,Department of Surgery, Division of Thoracic Surgery
[10] China Medical University Hospital,Management Office for Health Data
[11] China Medical University,College of Medicine
[12] China Medical University,Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine
[13] China Medical University Hospital,Department of Radiation Oncology
来源：
European Journal of Clinical Microbiology & Infectious Diseases | 2017年 / 36卷
关键词：
Radical Prostatectomy; Herpes Zoster; National Health Insurance Research Database; National Health Insurance Program; Herpes Zoster Infection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The present study investigated the association between radical prostatectomy (RP) and the risk of herpes zoster (HZ). Male patients aged ≥ 40 years and diagnosed with prostate cancer (PCa) between 2000 and 2005 were included in this study. Patients who underwent RP for the first time during 2000–2006 were included in the RP group. Randomly selected individuals from among the remaining patients with PCa who did not undergo RP were included in the non-RP group. Univariate and multivariate Cox regression models were used to analyze the association between PCa and HZ. In addition, the association between RP and the risk of HZ in different subgroups was evaluated after stratification by age, comorbidities, and hormone therapy (HoT) status. Furthermore, the combined effect of RP and HoT on the risk of HZ was evaluated. This study included 1,380 patients with PCa who newly underwent RP and 1,371 patients with PCa who did not undergo RP. During follow-up, 96 and 104 patients in the RP and non-RP groups, respectively, developed HZ. Patients who underwent both RP and HoT showed a significantly reduced risk of HZ, compared with patients who did not undergo both RP and HoT. RP is not associated with an increased risk of HZ. However, prostate-specific antigen levels should be monitored routinely during follow-up to detect PCa recurrence.
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页码：337 / 342
页数：5
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