Circ_0114428 knockdown inhibits ROCK2 expression to assuage lipopolysaccharide-induced human pulmonary alveolar epithelial cell injury through miR-574-5p

被引：0
|
作者：
Jing Zhao
Qin Zhao
Qiuxia Duan
机构：
[1] Yantai City Yantaishan Hospital,Department of Critical Care Medicine
[2] Weifang People’s Hospital,Emergency Internal Medicine Department
[3] The Third People’s Hospital of Qingdao,Department of Critical Care Medicine
来源：
The Journal of Physiological Sciences | / 74卷
关键词：
ALI; circ_0114428; miR-574-5p; ROCK2; LPS;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Circ_0114428 was upregulated in the blood samples of sepsis patients.LPS treatment increased circ_0114428 expression in HPAEpiCs.Knockdown of circ_0114428 ameliorated LPS-induced lung cell injury.Circ_0114428 modulated ROCK2 expression through miR-574-5p.
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