Multicenter validation of the value of BASFI and BASDAI in Chinese ankylosing spondylitis and undifferentiated spondyloarthropathy patients

被引：0
作者：
Zhiming Lin
Jieruo Gu
Peigen He
Jiesheng Gao
Xiaoxia Zuo
Zhizhong Ye
Fengmin Shao
Feng Zhan
Jinying Lin
Li Li
Yanlin Wei
Manlong Xu
Zetao Liao
Qu Lin
机构：
[1] The Third Affiliated Hospital of Sun Yat-sen University,Department of Rheumatology
[2] Central China University of Science and Technology,Department of Rheumatology, Tongji Hospital, Tongji Medical College
[3] Central South University,Department of Rheumatology, Xiangya Second Affiliated Hospital
[4] Central South University,Department of Rheumatology, Xiangya First Affiliated Hospital
[5] Shenzhen Rheumatology Institute of Guangdong Medical College,Department of Rheumatology
[6] Henan Provincial People’s Hospital,Department of Rheumatology
[7] Hainan Provincial People’s Hospital,Department of Rheumatology
[8] Guangxi Zhuangzu Autonomous Region People’s Hospital,undefined
来源：
Rheumatology International | 2011年 / 31卷
关键词：
Ankylosing spondylitis; BASDAI; BASFI; Reliability;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The objectives of this study were to evaluate the reliability of Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis disease activity index (BASDAI) in Chinese ankylosing spondylitis (AS) and undifferentiated spondyloarthropathy (USpA) patients. 664 AS patients by the revised New York criteria for AS and 252 USpA patients by the European Spondyloarthropathy Study Group criteria were enrolled. BASDAI and BASFI questionnaires were translated into Chinese. Participants were required to fill in BASFI and BASDAI questionnaires again after 24 h. Moreover, BASDAI and BASFI were compared in AS patients receiving Enbrel or infliximab before and after treatment. For AS group, BASDAI ICC: 0.9502 (95% CI: 0.9330–0.9502, α = 0.9702), BASFI ICC: 0.9587 (95% CI: 0.9521–0.9645, α = 0.9789). For USpA group, BASDAI ICC: 0.9530 (95% CI: 0.9402–0.9632, α = 0.9760), BASFI ICC: 0.9900 (95% CI: 0.9871–0.9922, α = 0.9950). In the AS group, disease duration, occipital wall distance, modified Schober test, chest expansion, ESR, and CRP showed significant correlation with BASDAI and BASFI (all P < 0.01). In the USpA group, onset age, ESR, and CRP were significantly correlated with BASDAI (all P < 0.05), while modified Schober test, ESR, and CRP were significantly associated with BASFI (all P < 0.05). The change in BASDAI and BASFI via Enbrel or infliximab treatment showed a significant positive correlation (P < 0.01). The two instruments have good reliability and reference value regarding the evaluation of patient’s condition and anti-TNF-α treatment response.
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页码：233 / 238
页数：5
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