Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway

[1] Miyara M(2007)Natural regulatory T cells: mechanisms of suppression Trends Mol Med 13 108-16

[2] Sakaguchi S(2006)Activated CD4+CD25+ T cells selectively kill B lymphocytes Blood 107 3925-32

[3] Zhao DM(2005)Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism J Immunol 174 1783-6

[4] Thornton AM(2007)Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance Immunity 27 635-46

[5] DiPaolo RJ(2008)Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells J Immunol 181 4752-60

[6] Shevach EM(2008)In vitro expansion improves in vivo regulation by CD4+CD25+ regulatory T cells J Immunol 180 858-69

[7] Gondek DC(1993)Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Cell 75 253-61

[8] Lu LF(1995)Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta Science 268 1472-6

[9] Quezada SA(1995)Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells Eur J Immunol 25 3053-9

[10] Sakaguchi S(2007)IL-2Rbeta links IL-2R signaling with Foxp3 expression Eur J Immunol 37 1817-26

[1] Miyara M(2007)Natural regulatory T cells: mechanisms of suppression Trends Mol Med 13 108-16

[2] Sakaguchi S(2006)Activated CD4+CD25+ T cells selectively kill B lymphocytes Blood 107 3925-32

[3] Zhao DM(2005)Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism J Immunol 174 1783-6

[4] Thornton AM(2007)Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance Immunity 27 635-46

[5] DiPaolo RJ(2008)Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells J Immunol 181 4752-60

[6] Shevach EM(2008)In vitro expansion improves in vivo regulation by CD4+CD25+ regulatory T cells J Immunol 180 858-69

[7] Gondek DC(1993)Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Cell 75 253-61

[8] Lu LF(1995)Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta Science 268 1472-6

[9] Quezada SA(1995)Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells Eur J Immunol 25 3053-9

[10] Sakaguchi S(2007)IL-2Rbeta links IL-2R signaling with Foxp3 expression Eur J Immunol 37 1817-26