New cyclometalated transition-metal based photosensitizers for singlet oxygen generation and photodynamic therapy

被引：0
作者：
Xinpeng Jiang
Ningbo Zhu
Dahui Zhao
Yuguo Ma
机构：
[1] Center for Soft Matter Science and Engineering,Beijing National Laboratory for Molecular Sciences
[2] Key Lab of Polymer Chemistry and Physics of the Ministry of Education,undefined
[3] College of Chemistry,undefined
[4] Peking University,undefined
来源：
Science China Chemistry | 2016年 / 59卷
关键词：
photosensitizer; singlet oxygen; photodynamic therapy; cyclometalated; transition-metal complexes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The aim of this review article is to introduce recent studies on an emergent class of singlet oxygen photosensitizers of potential applications to the photodynamic therapy, with a primary focus on the cyclometalated transition-metal complexes. Singlet oxygen photosensitization performances of various cyclometalated Ir and Pt scaffolds are reviewed, and the general photophysical properties of relevant systems and the mechanisms of singlet oxygen production via photo-sensitization are also briefly discussed. Thus far, investigations of singlet oxygen sensitization by such Ir and Pt complexes are mainly carried out in organic solvents and under non-physiological conditions, while some research efforts have been made at examining the feasibility of applying pertinent cyclometalated complexes to photodynamic therapy.
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页码：40 / 52
页数：12
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