Safety and efficacy of glibenclamide combined with rtPA in acute cerebral ischemia with occlusion/stenosis of anterior circulation (SE-GRACE): study protocol for a randomized controlled trial

被引：0
作者：
Kaibin Huang
Zhong Ji
Yongming Wu
Yunqiang Huang
Guangning Li
Saijun Zhou
Zhi Yang
Wenguo Huang
Guoshuai Yang
Guohu Weng
Pingyan Chen
Suyue Pan
机构：
[1] Southern Medical University,Department of Neurology, Nanfang Hospital
[2] Heyuan People’s Hospital,Department of Neurology
[3] Huadu district People’s Hospital,Department of Neurology
[4] The First Affiliated Hospital of Wenzhou Medical University,Department of Neurology
[5] Maoming People’s Hospital,Department of Neurology
[6] Maoming Hospital of Traditional Chinese Medicine,Department of Neurology
[7] Haikou People’s Hospital,Department of Neurology
[8] Hainan Hospital of Traditional Chinese Medicine,Department of Neurology
[9] School of Public Health,Department of Biostatistics
[10] Southern Medical University,undefined
来源：
BMC Neurology | / 20卷
关键词：
Combined treatment; Glibenclamide; Randomized controlled trial; Stroke;
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[1]  
Lozano R(2012)Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010 Lancet. 380 2095-2128
[2]  
Naghavi M(2013)Global stroke statistics Int J Stroke 9 6-18
[3]  
Foreman K(2014)Thrombolysis for acute ischaemic stroke Cochrane Database Syst Rev 7 D213-219
[4]  
Lim S(2010)Current and future recanalization strategies for acute ischemic stroke J Intern Med 267 209-3035
[5]  
Shibuya K(2015)2015 american heart association/American stroke association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment Stroke. 46 3020-440
[6]  
Aboyans V(2006)Newly expressed SUR1-regulated NC (Ca-ATP) channel mediates cerebral edema after ischemic stroke Nat Med 12 433-609
[7]  
Thrift AG(2009)Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke Stroke. 40 604-295
[8]  
Cadilhac DA(2012)Glibenclamide-10-h treatment window in a clinically relevant model of stroke Transl Stroke Res 3 286-2530
[9]  
Thayabaranathan T(2007)Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke Stroke. 38 2526-806
[10]  
Howard G(2012)Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas Ann Neurol 72 799-1169
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