Membrane proteins bind lipids selectively to modulate their structure and function

被引：0
|
作者：
Arthur Laganowsky
Eamonn Reading
Timothy M. Allison
Martin B. Ulmschneider
Matteo T. Degiacomi
Andrew J. Baldwin
Carol V. Robinson
机构：
[1] University of Oxford,Department of Chemistry
[2] South Parks Road,Department of Materials Science and Engineering
[3] Oxford OX1 5QY,undefined
[4] UK,undefined
[5] Johns Hopkins University,undefined
来源：
Nature | 2014年 / 510卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new mass-spectrometry method has been developed to obtain high-resolution spectra of folded proteins bound to lipids; using this technique as well as X-ray crystallography provides evidence for membrane protein conformational change as a result of lipid–protein interaction.
引用
收藏
页码：172 / 175
页数：3
相关论文
共 50 条
  • [21] Structure and function of photosynthetic membrane proteins
    Fromme, Petra
    Yu, HongQi
    Fromme, Raimund
    Chauhan, Devendra K.
    Varco-Merth, Ben
    Lawrence, Robert
    DeRuytet, Yana
    Jolley, Craig
    Thangaraj, Balakumar
    Vanselow, Christopher
    Grotjohann, Ingo
    Bottin, Herve
    Setif, Pierre
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2008, 1777 : S21 - S21
  • [22] Role of Lipids in Folding, Misfolding and Function of Integral Membrane Proteins
    Hong, Heedeok
    LIPIDS IN PROTEIN MISFOLDING, 2015, 855 : 1 - 31
  • [23] Cell penetrating compounds selectively bind vesicles composed of anionic lipids
    Benish, Nicolas C.
    King, Tess
    Prevette, Lisa E.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [24] Bovine oviduct epithelial cell-surface proteins bind to sperm and modulate their function.
    Boilard, M
    Sirard, MA
    Bailey, JL
    Leclerc, P
    BIOLOGY OF REPRODUCTION, 2002, 66 : 279 - 279
  • [25] Effects of membrane lipids on ion channel structure and function
    Tommy S. Tillman
    Michael Cascio
    Cell Biochemistry and Biophysics, 2003, 38 : 161 - 190
  • [26] Effects of membrane lipids on ion channel structure and function
    Tillman, TS
    Cascio, M
    CELL BIOCHEMISTRY AND BIOPHYSICS, 2003, 38 (02) : 161 - 190
  • [27] MEMBRANE LIPIDS AND CONFORMATIONS OF MEMBRANE PROTEINS
    WALLACH, DFH
    JOURNAL OF GENERAL PHYSIOLOGY, 1969, 54 (1P2): : S3 - +
  • [28] Resurfaced Shape Complementary Proteins That Selectively Bind the Oncoprotein Gankyrin
    Chapman, Alex M.
    McNaughton, Brian R.
    ACS CHEMICAL BIOLOGY, 2014, 9 (10) : 2223 - 2228
  • [29] ROTATIONAL AND LATERAL DIFFUSION OF MEMBRANE-PROTEINS AND LIPIDS - PHENOMENA AND FUNCTION
    EDIDIN, M
    CURRENT TOPICS IN MEMBRANES AND TRANSPORT, 1987, 29 : 91 - 127
  • [30] Membrane proteins of photosynthesis:: Structure function biotechnology
    Rögner, M
    Berry, S
    Boronowsky, U
    Flueren, A
    Jäger, C
    Kuhl, H
    Schneider, D
    Seidler, A
    Wenk, SO
    Karapetyan, N
    Kruip, J
    CHLOROPLAST: FROM MOLECULAR BIOLOGY TO BIOTECHNOLOGY, 1999, 64 : 305 - 310
12345