Human ASPM participates in spindle organisation, spindle orientation and cytokinesis

[1] Rakic P(1978)Neuronal migration and contact guidance in the primate telencephalon Postgrad Med J 54 25-40

[2] Lu B(2000)Control of cell divisions in the central nervous system: symmetry and asymmetry Ann Rev Neurosci 23 531-556

[3] Jan L(1995)Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis Cell 82 631-641

[4] Jan YN(2002) is a major determinant of cerebral cortical size Nat Genet 32 316-320

[5] Chenn A(2000)Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex Mol Cell Biol 20 7813-7825

[6] McConnell SK(2002)Identification of microcephalin, a protein implicated in determining the size of the human brain Am J Hum Genet 71 136-142

[7] Bond J(2005)The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein Hum Mol Genet 14 2155-2165

[8] Roberts E(2005)A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size Nat Genet 37 353-355

[9] Mochida GH(2006)Regulation of mitotic entry by microcephalin and its overlap with ATR signalling Nat Cell Biol 8 725-733

[10] Hampshire DJ(2007)MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage J Biol Chem 282 35416-35423

[1] Rakic P(1978)Neuronal migration and contact guidance in the primate telencephalon Postgrad Med J 54 25-40

[2] Lu B(2000)Control of cell divisions in the central nervous system: symmetry and asymmetry Ann Rev Neurosci 23 531-556

[3] Jan L(1995)Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis Cell 82 631-641

[4] Jan YN(2002) is a major determinant of cerebral cortical size Nat Genet 32 316-320

[5] Chenn A(2000)Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex Mol Cell Biol 20 7813-7825

[6] McConnell SK(2002)Identification of microcephalin, a protein implicated in determining the size of the human brain Am J Hum Genet 71 136-142

[7] Bond J(2005)The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein Hum Mol Genet 14 2155-2165

[8] Roberts E(2005)A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size Nat Genet 37 353-355

[9] Mochida GH(2006)Regulation of mitotic entry by microcephalin and its overlap with ATR signalling Nat Cell Biol 8 725-733

[10] Hampshire DJ(2007)MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage J Biol Chem 282 35416-35423