Islet Cell Transplantion: Update on Current Clinical Trials

被引：12
作者：
Schuetz C. [1 ]
Markmann J.F. [1 ]
机构：
[1] Islet Transplantation Laboratory, Division of Transplantation, Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Thier 807a, Boston, 02114, MA
来源：
Current Transplantation Reports | 2016年 / 3卷 / 3期
关键词：
Clinical outcomes; Clinical trials; Immunosuppression; Pancreatic islet transplantation; Registry; Type 1 diabetes mellitus;
D O I：
10.1007/s40472-016-0103-z
中图分类号：
学科分类号：
摘要：
In the last 15 years, clinical islet transplantation has made the leap from experimental procedure to standard of care for a highly selective group of patients. Due to a risk/benefit calculation involving the required systemic immunosuppression, the procedure is only considered in patients with type 1 diabetes, complicated by severe hypoglycemia or end stage renal disease. In this review, we summarize current outcomes of the procedure and take a look at ongoing and future improvements and refinements of beta cell therapy. © 2016, Springer International Publishing AG.
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页码：254 / 263
页数：9
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