Treatment of Malignant Brain Edema and Increased Intracranial Pressure After Stroke

被引:0
作者
Michael E. Brogan
Edward M. Manno
机构
[1] Cleveland Clinic,Neurological Intensive Care Unit, Cerebrovascular Center
[2] Cleveland Clinic Lerner College of Medicine and Case Western Reserve University,Neurological Intensive Care Unit, Cleveland Clinic
来源
Current Treatment Options in Neurology | 2015年 / 17卷
关键词
Patient care management; Stroke; Infarction; Brain edema; Malignant cerebral edema; Intracranial pressure; Decompressive craniectomy;
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学科分类号
摘要
The management of patients with large territory ischemic strokes and the subsequent development of malignant brain edema and increased intracranial pressure is a significant challenge in modern neurology and neurocritical care. These patients are at high risk of subsequent neurologic decline and are best cared for in an intensive care unit or a comprehensive stroke center with access to neurosurgical support. Risks include hemorrhagic conversion, herniation, poor functional outcome, and death. This review discusses recent advances in understanding the pathophysiology of edema formation, identifying patients at risk, current management strategies, and emerging therapies.
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