FIT Testing: An Overview

被引:16
作者
Lukejohn W. Day
Taft Bhuket
James Allison
机构
[1] San Francisco General Hospital and Trauma Center,Division of Gastroenterology, Department of Medicine
[2] Alameda Health System,Division of Gastroenterology, Department of Medicine
[3] University of California,Division of Gastroenterology
[4] San Francisco,undefined
[5] Kaiser Permanente Northern California Division of Research,undefined
关键词
Fecal immunochemical testing; Colorectal cancer screening; Quality; Fecal occult blood;
D O I
10.1007/s11894-013-0357-x
中图分类号
学科分类号
摘要
Colorectal cancer (CRC) is a common, but preventable, disease and is the second most common cause of cancer-related deaths in the U.S. CRC screening has proven effective at reducing both the incidence and mortality of this disease, using any of a number of screening tests available. The test options range from the least invasive and least expensive to more invasive and costly options. Fecal occult blood testing is the oldest, least expensive, and least invasive of these options and has evolved from the poorly sensitive standard guaiac test to the newer and diagnostically superior fecal immunochemical test (FIT) for hemoglobin. This article explores the evolutionary history of fecal occult blood testing, examines test performance characteristics among different FOBTs, and evaluates the role of the FIT in programmatic CRC screening.
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  • [1] Siegel R(2012)Cancer treatment and survivorship statistics, 2012 CA Cancer J Clin 62 220-41
  • [2] DeSantis C(1985)Occult blood screening for colorectal carcinoma: a critical review Gastroenterology 88 820-37
  • [3] Virgo K(1965)Routine chemical tests of the stool for occult blood: an evaluation Am J Med Sci 249 247-60
  • [4] Stein K(1967)Diagnosis of large-bowel cancer in the asymptomatic patient JAMA 201 943-5
  • [5] Mariotto A(2004)Reduction in colorectal cancer mortality by fecal occult blood screening in a French controlled study Gastroenterology 126 1674-80
  • [6] Smith T(1996)Randomised controlled trial of faecal-occult-blood screening for colorectal cancer Lancet 348 1472-7
  • [7] Simon JB(1996)Randomised study of screening for colorectal cancer with faecal-occult-blood test Lancet 348 1467-71
  • [8] Irons GV(2008)Survival benefit in a randomized clinical trial of faecal occult blood screening for colorectal cancer Br J Surg 95 1029-36
  • [9] Kirsner JB(1993)Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study N Engl J Med 328 1365-71
  • [10] Greegor DH(2001)Does stool collection method affect outcomes in immunochemical fecal occult blood testing? Dis Colon Rectum 44 871-5