The absence of AhR in CD4+ T cells in patients with acute graft-versus-host disease may be related to insufficient CTCF expression

被引:0
作者
Cong Zeng
Ting-ting Cheng
Xia Ma
Yi Liu
Juan Hua
Xu Chen
Shi-yu Wang
Ya-jing Xu
机构
[1] Central South University,Department of Hematology, Xiangya Hospital
[2] Xiangya Hospital,National Clinical Research Center for Geriatric Diseases
[3] Hunan Hematology Oncology Clinical Medical Research Center,National Clinical Research Center for Hematologic Diseases
[4] The First Affiliated Hospital of Soochow University,undefined
来源
Clinical Epigenetics | 2022年 / 14卷
关键词
aGVHD; AhR; CTCF; TET2; EP300;
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[41]  
Shu Y(2010)The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27 Nat Immunol 11 310-1010
[42]  
Li X(2017)Is chronic AhR activation by rapidly metabolized ligands safe for the treatment of immune-mediated diseases? Curr Opin Toxicol 2 5695-66
[43]  
Zhao X(2017)AhR activation increases IL-2 production by alloreactive CD4(+) T cells initiating the differentiation of mucosal-homing Tim3(+) Lag3(+) Tr1 cells Eur J Immunol 47 1704-1177
[44]  
Chen F(2010)Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells Nat Immunol 11 20398-45
[45]  
Zeiser R(1950)Dietary indoles suppress delayed-type hypersensitivity by inducing a switch from proinflammatory Th17 cells to anti-inflammatory regulatory T cells through regulation of microrna J Immunol (Baltimore MD) 196 999-263
[46]  
Socie G(2018)TCDD, FICZ, and other high affinity AhR ligands dose-dependently determine the fate of CD4+ T cell differentiation Toxicol Sci Off J Soc Toxicol 161 56-304
[47]  
Blazar BR(2019)Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites Nat Commun 10 1173-828
[48]  
Zitzer NC(2020)Metabolic reprogramming-a new era how to prevent and treat graft versus host disease after allogeneic hematopoietic stem cell transplantation has begun Front Pharmacol 11 38-g230
[49]  
Snyder K(2015)CTCF recruits centromeric protein CENP-E to the pericentromeric/centromeric regions of chromosomes through unusual CTCF-binding sites Cell Rep 12 251-undefined
[50]  
Meng X(2008)CTCF-dependent enhancer-blocking by alternative chromatin loop formation Proc Natl Acad Sci U S A 105 2011-undefined