The Role of CD4+CD25+ T Regulatory Cells in Autoimmune Diseases

被引：0
|
作者：
E. Toubi
机构：
[1] Bnai-Zion Medical Center,Division of Allergy and Clinical Immunology
[2] Technion,Division of Allergy and Clinical Immunology
[3] Rapaport,undefined
[4] Faculty of Medicine,undefined
[5] Bnai-Zion Medical Center,undefined
来源：
Clinical Reviews in Allergy & Immunology | 2008年 / 34卷
关键词：
T regulatory cells; Autoimmune diseases;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Among the several mechanisms that play role in maintaining peripheral self-tolerance is the existence of a unique CD4+CD25+ population of naturally occurring regulatory T (Treg) cells that actively prevent both the activation and the effector function of autoreactive T cells that have escaped different mechanisms of tolerance. Many studies have shown the benefit of targeting this cell population by restoring self-tolerance. Therapies that could possibly increase the suppressive ability of T regulatory cells were proven to improve that course of autoimmune diseases.
引用
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页码：338 / 344
页数：6
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