Comparative Efficacy of Vildagliptin and Sitagliptin in Japanese Patients with Type 2 Diabetes MellitusA Matching-Adjusted Indirect Comparison of Randomized Trials
Background and Objective: Vildagliptin and sitagliptin are oral dipeptidyl peptidase 4 inhibitors approved in Japan for the treatment of type 2 diabetes mellitus when adequate glycaemic control is not achieved with diet, exercise or sulphonylureas. The aim of this study was to compare 12-week glycaemic control with vildagliptin 50 mg twice daily versus sitagliptin 50 or 100 mg once daily in Japanese patients with type 2 diabetes.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Tanaka M.
Sekioka R.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Sekioka R.
Nishimura T.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Nishimura T.
Kawai T.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Kawai T.
Meguro S.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Meguro S.
Irie J.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Irie J.
Saisho Y.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
Saisho Y.
Itoh H.
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Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, TokyoDepartment of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo
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Univ Copenhagen, Gentofte Hosp, Dept Internal Med F, Diabet Res Div, Copenhagen, DenmarkMerck Res Labs, Rahway, NJ 07065 USA
Vilsboll, T.
Rosenstock, J.
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Dallas Diabet & Endocrine Ctr Med City, Dallas, TX USAMerck Res Labs, Rahway, NJ 07065 USA
Rosenstock, J.
Yki-Jarvinen, H.
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Univ Helsinki, HUCH, Helsinki, FinlandMerck Res Labs, Rahway, NJ 07065 USA
Yki-Jarvinen, H.
Cefalu, W. T.
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Louisiana State Univ, Hlth Sci Ctr, Baton Rouge, LA 70803 USA
Louisiana State Univ, Hlth Sci Ctr, New Orleans, LA USA
Pennington Biomed Res Ctr, New Orleans, LA USA
Pennington Biomed Res Ctr, Baton Rouge, LA USAMerck Res Labs, Rahway, NJ 07065 USA
Cefalu, W. T.
Chen, Y.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Chen, Y.
Luo, E.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Luo, E.
Musser, B.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Musser, B.
Andryuk, P. J.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Andryuk, P. J.
Ling, Y.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Ling, Y.
Kaufman, K. D.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Kaufman, K. D.
Amatruda, J. M.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Amatruda, J. M.
Engel, S. S.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Engel, S. S.
Katz, L.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
机构:
Dr Mohans Diabet Special Ctr, Madras 600086, Tamil Nadu, India
Madras Diabet Res Fdn, Madras 600086, Tamil Nadu, IndiaMerck Res Labs, Rahway, NJ 07065 USA
Mohan, Viswanathan
Yang, Wenying
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China Japan Friendship Hosp, Beijing, Peoples R ChinaMerck Res Labs, Rahway, NJ 07065 USA
Yang, Wenying
Son, Ho-Young
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Catholic Univ Korea, Coll Med, Div Endocrinol & Metab, Seoul, South KoreaMerck Res Labs, Rahway, NJ 07065 USA
Son, Ho-Young
Xu, Lei
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Xu, Lei
Noble, Liliane
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Noble, Liliane
Langdon, Ronald B.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Langdon, Ronald B.
Amatruda, John M.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Amatruda, John M.
Stein, Peter P.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
Stein, Peter P.
Kaufman, Keith D.
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Merck Res Labs, Rahway, NJ 07065 USAMerck Res Labs, Rahway, NJ 07065 USA
机构:
Tokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, JapanTokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, Japan
Odawara, Masato
Yoshiki, Mika
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机构:
Novartis Pharma KK, Tokyo, JapanTokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, Japan
Yoshiki, Mika
Sano, Misako
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机构:
Novartis Pharma KK, Tokyo, JapanTokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, Japan
Sano, Misako
Hamada, Izumi
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机构:
Novartis Pharma KK, Tokyo, JapanTokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, Japan
Hamada, Izumi
Lukashevich, Valentina
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Nova Pharmaceut Corp, E Hanover, NJ USATokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, Japan
Lukashevich, Valentina
Kothny, Wolfgang
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Novartis Pharma AG, Basel, SwitzerlandTokyo Med Univ, Dept Diabet Endocrinol Metab & Rheumatol, Tokyo 1608402, Japan