Delivery of oncolytic vaccinia virus by matched allogeneic stem cells overcomes critical innate and adaptive immune barriers

被引:0
作者
Dobrin D. Draganov
Antonio F. Santidrian
Ivelina Minev
Duong Nguyen
Mehmet Okyay Kilinc
Ivan Petrov
Anna Vyalkova
Elliot Lander
Mark Berman
Boris Minev
Aladar A. Szalay
机构
[1] Calidi Biotherapeutics,Institute of Biochemistry, Biocentre
[2] University of Wuerzburg,Radiation Oncology, Moores Cancer Center
[3] University of California San Diego,undefined
[4] California Stem Cell Treatment Center,undefined
来源
Journal of Translational Medicine | / 17卷
关键词
Vaccinia; Cancer; Stem Cells; Oncolysis; Oncolytic virus; Virotherapy; Immunity; Immunotherapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 421 条
[31]  
Traktuev DO(2007)Synergism of MSC-secreted HGF and VEGF in stabilising endothelial barrier function upon lipopolysaccharide stimulation via the Rac1 pathway Hepatology 46 219-10
[32]  
Amaya-Manzanares F(2007)Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes Stem Cells. 25 3234-396
[33]  
Simmons PJ(2016)Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization Sci Rep. 6 37566-234
[34]  
March KL(2009)Umbilical cord-derived mesenchymal stem cells instruct monocytes towards an IL10-producing phenotype by secreting IL6 and HGF In Vivo. 23 21-222
[35]  
Aggarwal S(2014)In vitro and in vivo immunosuppressive characteristics of hepatocyte growth factor-modified murine mesenchymal stem cells Oncogene 33 3830-84
[36]  
Pittenger MF(2015)P53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation Oncogene 2016 1-1311
[37]  
Coulson-Thomas VJ(2014)Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells Cell Death Differ 21 388-648
[38]  
Coulson-Thomas YM(2007)Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species Blood 109 228-5148
[39]  
Gesteira TF(2008)Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells Stem Cells. 26 212-1446
[40]  
Kao WW-Y(2011)Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD Scand J Immunol 73 79-141