Management of pulmonary aspergillosis in children: a systematic review

被引：0
作者：
Vito Terlizzi
Marco Antonio Motisi
Roberta Pellegrino
Luisa Galli
Giovanni Taccetti
Elena Chiappini
机构：
[1] Meyer Children’s Hospital IRCCS,Cystic Fibrosis Regional Reference Center, Department of Paediatric Medicine
[2] Meyer Children’s University Hospital IRCCS,Pediatrics resident, Department of Health Sciences
[3] University of Florence,Infectious Diseases Unit, Department of Health Sciences
[4] Meyer Children’s University Hospital IRCCS,undefined
[5] University of Florence,undefined
来源：
Italian Journal of Pediatrics | / 49卷
关键词：
PULMONARY aspergillosis; Children; Galactomannan; β-D-glucan; Voriconazole;
D O I：
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中图分类号：
学科分类号：
摘要：
Invasive pulmonary aspergillosis (IPA) is a severe condition in immunocompromised children, but the optimal management is still under debate. In order to better clarify this issue, a literature search was performed through MEDLINE/PubMed database to describe current risk factors and diagnostic, therapeutic and prophylactic tools for invasive pulmonary aspergillosis (IPA) in the paediatric age. Observational studies and clinical trials regarding diagnosis, treatment and prophylaxis were considered, and results were summarised. Five clinical trials and 25 observational studies (4453 patients) were included.
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