Genomics in the era of COVID-19: ethical implications for clinical practice and public health

被引：0

作者：

Gail Geller

Priya Duggal

Chloe L. Thio

Debra Mathews

Jeffrey P. Kahn

Lisa L. Maragakis

Brian T. Garibaldi

机构：

[1] Johns Hopkins University,Berman Institute of Bioethics

[2] Johns Hopkins University School of Medicine,undefined

[3] Johns Hopkins Bloomberg School of Public Health,undefined

[4] Johns Hopkins School of Medicine Hepatitis Center,undefined

[5] Johns Hopkins School of Medicine Infection Control,undefined

[6] Johns Hopkins University School of Medicine Pulmonology,undefined

来源：

Genome Medicine | / 12卷

关键词：

COVID-19; Ethics; Host genomics;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Genomic studies of patients with COVID-19, or exposed to it, are underway to delineate host factors associated with variability in susceptibility, infectivity, and disease severity. Here, we highlight the ethical implications—both potential benefits and harms—of genomics for clinical practice and public health in the era of COVID-19.

引用

共 22 条

[1] Horby P(2012)The role of host genetics in susceptibility to influenza: a systematic review PLoS One 7 e33180-718
[2] Nguyen NY(2020)The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic Eur J Hum Genet 28 715-3
[3] Dunstan SJ(2020)Societal considerations in host genome testing for COVID-19 Genet Med 8 1-40
[4] Baillie JK(2014)Genomics and infectious disease: a call to identify the ethical, legal, and social implications for public health and clinical practice Genome Med 6 106-e01918
[5] Milne R(2020)Genomics and infectious diseases: expert perspectives on public health considerations regarding actionability and privacy Ethics Hum Res 42 30-984
[6] Geller G(2019)Societal implications of the internet of pathogens J Clin Microbiol 57 e01914-undefined
[7] Dvoskin R(2018)Direct-acting antivirals and hepatitis C: the ethics of price and rationing by genotype Clin Infect Dis 67 983-undefined
[8] Thio CL(undefined)undefined undefined undefined undefined-undefined
[9] Duggal P(undefined)undefined undefined undefined undefined-undefined
[10] Lewis MH(undefined)undefined undefined undefined undefined-undefined

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