Mouse mesenchymal stem cell-derived exosomal miR-466f-3p reverses EMT process through inhibiting AKT/GSK3β pathway via c-MET in radiation-induced lung injury

被引：0
|
作者：
Yi Li
Zhufu Shen
Xiao Jiang
Yuanyuan Wang
Zuozhang Yang
Yuchi Mao
Zhixian Wu
Gaofeng Li
Hong Chen
机构：
[1] 920th Hospital of Joint Logistics Support Force,Department of Oncology
[2] Teaching Hospital of Kunming Medical University,Department of Geriatrics
[3] 920th Hospital of Joint Logistics Support Force,Department of Pathology
[4] Teaching Hospital of Kunming Medical University,Department of Orthopaedics
[5] 920th Hospital of Joint Logistics Support Force,Department of Hepatobiliary Disease
[6] Teaching Hospital of Kunming Medical University,Department of Thoracic Surgery
[7] The Third Affiliated Hospital of Kunming Medical University,undefined
[8] 900th Hospital of Joint Logistics Support Force,undefined
[9] The Third Affiliated Hospital of Kunming Medical University,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 41卷
关键词：
Radiation-induced lung fibrosis; Epithelial-mesenchymal transition; Exosome; Mesenchymal stem cells; miR-466f-3p;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 30 条
  • [21] Mouse mesenchymal stem cell-derived exosomal miR-205-5p modulates LPS-induced macrophage polarization and alleviates lung injury by regulating the USP7/FOXM1 axis
    Feng, Yinglu
    Tang, Min
    Li, Haopeng
    Yao, Shanglong
    Li, Bo
    DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2025,
  • [22] Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Protect Cardiomyocytes from Doxorubicin-Induced Cardiomyopathy by Upregulating Survivin Expression via the miR-199a-3p-Akt-Sp1/p53 Signaling Pathway
    Lee, Ji Yoon
    Chung, Jihwa
    Byun, Yeongju
    Kim, Kyoung Hwa
    An, Shung Hyun
    Kwon, Kihwan
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (13)
  • [23] Hypoxia-elicited cardiac microvascular endothelial cell-derived exosomal miR-210-3p alleviate hypoxia/reoxygenation-induced myocardial cell injury through inhibiting transferrin receptor 1-mediated ferroptosis
    Lei, Dongyu
    Li, Biao
    Isa, Zuribia
    Ma, Xiaoqiang
    Zhang, Baojian
    TISSUE & CELL, 2022, 79
  • [24] Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway (vol 17, 46, 2020)
    Hou, Kun
    Li, Guichen
    Zhao, Jinchuan
    Xu, Baofeng
    Zhang, Yang
    Yu, Jinlu
    Xu, Kan
    JOURNAL OF NEUROINFLAMMATION, 2020, 17 (01)
  • [25] Bone Marrow Mesenchymal Stem Cell-Derived Microvesicles Protect Rat Pheochromocytoma PC12 Cells from Glutamate-Induced Injury via a PI3K/Akt Dependent Pathway
    Shan-Shan Lin
    Bo Zhu
    Zi-Kuan Guo
    Guo-Zhi Huang
    Zi Wang
    Jin Chen
    Xiao-Juan Wei
    Qi Li
    Neurochemical Research, 2014, 39 : 922 - 931
  • [26] Bone Marrow Mesenchymal Stem Cell-Derived Microvesicles Protect Rat Pheochromocytoma PC12 Cells from Glutamate-Induced Injury via a PI3K/Akt Dependent Pathway
    Lin, Shan-Shan
    Zhu, Bo
    Guo, Zi-Kuan
    Huang, Guo-Zhi
    Wang, Zi
    Chen, Jin
    Wei, Xiao-Juan
    Li, Qi
    NEUROCHEMICAL RESEARCH, 2014, 39 (05) : 922 - 931
  • [27] Human umbilical cord mesenchymal stem cell-derived extracellular vesicles alleviated silica induced lung inflammation and fibrosis in mice via circPWWP2A/miR-223-3p/NLRP3 axis
    Hou, Lin
    Zhu, Zhonghui
    Jiang, Fuyang
    Zhao, Jing
    Jia, Qiyue
    Jiang, Qiyue
    Wang, Hongwei
    Xue, Wenming
    Wang, Yan
    Tian, Lin
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 251
  • [28] miR-666-3p Mediates the Protective Effects of Mesenchymal Stem Cell-derived Exosomes Against Oxygen-glucose Deprivation and Reoxygenation-induced Cell Injury in Brain Microvascular Endothelial Cells via Mitogen-activated Protein Kinase Pathway
    Kong, Li-yun
    Li, Yan
    Rao, Ding-yu
    Wu, Bing
    Sang, Cheng-peng
    Lai, Ping
    Ye, Jun-song
    Zhang, Zu-xiong
    Du, Zhi-ming
    Yu, Jun-jian
    Gu, Liang
    Xie, Fa-chun
    Liu, Zi-you
    Tang, Zhi-xian
    CURRENT NEUROVASCULAR RESEARCH, 2021, 18 (01) : 20 - 77
  • [29] LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway
    Chen, Hanbin
    Xia, Wenzheng
    Hou, Meng
    STEM CELL RESEARCH & THERAPY, 2020, 11 (01)
  • [30] Correction to: LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway
    Hanbin Chen
    Wenzheng Xia
    Meng Hou
    Stem Cell Research & Therapy, 11
123