Metabolic syndrome among Sri Lankan adults: prevalence, patterns and correlates

被引:0
作者
Prasad Katulanda
Priyanga Ranasinghe
Ranil Jayawardana
Rezvi Sheriff
David R Matthews
机构
[1] University of Colombo,Diabetes Research Unit, Department of Clinical Medicine, Faculty of Medicine
[2] University of Oxford,Oxford Centre for Diabetes, Endocrinology and Metabolism
[3] University of Colombo,Department of Pharmacology, Faculty of Medicine
[4] Queensland University of Technology,Institute of Health and Biomedical Innovation
来源
Diabetology & Metabolic Syndrome | / 4卷
关键词
Diabetes mellitus; Metabolic syndrome; Prevalence; Sri Lanka; Developing country; South Asia;
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摘要
Metabolic Syndrome (MS) increases the risk for Coronary Artery Disease, stroke and diabetes. MS is twice more common amongst South Asian immigrants in US compared to native Caucasians. There are no nationally representative studies on prevalence of MS from any of the South Asian countries. The present study aims to evaluate the prevalence of MS among Sri Lankan adults and investigates its relationships with socio-demographic, clinical and biochemical parameters. Data on MS and its associated details were obtained from a population-based cross-sectional study conducted between years 2005–2006. MS was defined according to the International Diabetes Federation criteria. A binary logistic regression analysis was performed using the dichotomous variable MS (0 = absent, 1 = present). The independent co-variants were: gender, age category, area of residence, ethnicity, level of education, income and physical activity. Sample size was 4,485 (Response rate–89.7%), 39.5% were males and mean age was 46.1 ± 15.1 years. The crude prevalence of MS was 27.1% (95% CI: 25.8–28.5), and age-adjusted prevalence was 24.3% (95% CI: 23.0–25.6). Prevalence in males and females were 18.4% (95% CI: 16.5–20.3) and 28.3% (95% CI: 26.6–30.0) respectively (p < 0.001). Urban adults (34.8% [95% CI: 31.8–37.9]) had a significantly higher prevalence than rural adults (21.6% [95% CI: 20.2–23.0]). Among ethnic groups, the highest prevalence of MS was observed in Sri Lankan Moors (43.0% [95% CI: 37.2–48.9]). In all adults, MS was observed in those with the highest level of education and monthly household income. Prevalence of MS in the different physical activity categories of the IPAQ were; ‘inactive’–38.8% (95% CI 34.5-43.2), ‘moderately active’–33.5% (95% CI 30.9-36.1) and ‘active’–21.1% (95% CI 19.6-22.7). The results of the binary logistic regression analysis indicates that female gender (OR:1.7), increasing age, urban living (OR:1.7), Moor ethnicity (OR:2.6), secondary (OR:1.5) and tertiary levels of education (OR:2.3), monthly household income LKR 7,000–24,999 (OR:1.5) and >50,000 (OR:2.1), and physical inactivity (OR:1.6), all significantly increased risk of developing MS. MS is common among Sri Lankan adults affecting nearly one-fourth of the population. Female gender, increasing age, urban living, higher socio-economical status and physical inactivity were important associated factors.
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  • [1] Grundy SM(2003)Inflammation, hypertension, and the metabolic syndrome JAMA 290 3000-3002
  • [2] Tabak AG(2009)Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study Lancet 373 2215-2221
  • [3] Jokela M(2008)The metabolic syndrome Endocr Rev 29 777-822
  • [4] Akbaraly TN(2006)Genetic determinants of the metabolic syndrome Nat Clin Pract Cardiovasc Med 3 482-489
  • [5] Brunner EJ(1996)Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America Indian Heart J 48 343-353
  • [6] Kivimaki M(2009)Coronary artery diseases in South Asian immigrants: an update on high density lipoprotein role in disease prevention J Immigr Minor Health 11 415-421
  • [7] Witte DR(2008)Excess coronary artery disease risk in South Asian immigrants: can dysfunctional high-density lipoprotein explain increased risk? Vasc Health Risk Manag 4 953-961
  • [8] Cornier MA(1998)Health status of Asian Americans: United States, 1992–94 Adv Data 7 1-16
  • [9] Dabelea D(2011)Metabolic syndrome in South Asian immigrants: more than low HDL requiring aggressive management Lipids Health Dis 10 45-514
  • [10] Hernandez TL(2009)The metabolic syndrome in South Asians: epidemiology, determinants, and prevention Metab Syndr Relat Disord 7 497-1069