Therapeutic application of hydrogen sulfide donors: the potential and challenges

被引:0
|
作者
Dan Wu
Qingxun Hu
Yizhun Zhu
机构
[1] Fudan University,Department of Pharmacology, School of Pharmacy
[2] Tongji University School of Medicine,Department of Pharmacy, Tongji Hospital
来源
Frontiers of Medicine | 2016年 / 10卷
关键词
hydrogen sulfide; cardiovascular; cancer; hypertension;
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学科分类号
摘要
Hydrogen sulfide (H2S), a colorless gas smelling of rotten egg, has long been considered a toxic gas and environment hazard. However, evidences show that H2S plays a great role in many physiological and pathological activities, and it exhibits different effects when applied at various doses. In this review, we summarize the chemistry and biomedical applications of H2S-releasing compounds, including inorganic salts, phosphorodithioate derivatives, derivatives of Allium sativum extracts, derivatives of thioaminoacids, and derivatives of antiinflammatory drugs.
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页码:18 / 27
页数:9
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