Effect of High Pressure on the Polymorphs of Paracetamol

被引:0
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作者
E. V. Boldyreva
T. P. Shakhtshneider
H. Ahsbahs
H. Sowa
H. Uchtmann
机构
[1] Siberian Department of Russian Academy of Sciences,Institute of Solid State Chemistry
[2] Novosibirsk State University,Center of Advanced Education ‘Molecular Design and Ecologically Advanced Technologies’
[3] Philips-Universität Marburg/Lahn,Center of Materials Sciences
关键词
diamond anvil cell; high pressure; hydrogen bonds; paracetamol; polymorphictransformations; polymorphs; X-ray diffraction;
D O I
10.1023/A:1016079400592
中图分类号
学科分类号
摘要
Effect of hydrostatic pressure on the two (I – monoclinic and II – orthorhombic) polymorphs of paracetamol was studied by X-ray diffraction in the diamond anvil cell at pressures up to 4.5 GPa (for the monoclinic form) and up to 5.5 GPa (for the orthorhombic form). The two groups of phenomena were studied: (i) the anisotropic structural distortion of the same polymorph, (ii) transitions between the polymorphs induced by pressure.
引用
收藏
页码:437 / 452
页数:15
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