Optogenetic protein clustering and signaling activation in mammalian cells

被引：0
|
作者：
Lukasz J Bugaj
Atri T Choksi
Colin K Mesuda
Ravi S Kane
David V Schaffer
机构：
[1] University of California,Department of Bioengineering
[2] Berkeley (UC Berkeley),Department of Chemical Engineering
[3] The UC Berkeley–UCSF Graduate Program in Bioengineering,Howard P. Isermann Department of Chemical and Biological Engineering
[4] UC Berkeley,undefined
[5] UC Berkeley,undefined
[6] Rensselaer Polytechnic Institute,undefined
[7] Center for Biotechnology and Interdisciplinary Studies,undefined
[8] Rensselaer Polytechnic Institute,undefined
[9] Helen Wills Neuroscience Institute,undefined
[10] UC Berkeley,undefined
[11] California Institute for Quantitative Biosciences,undefined
[12] UC Berkeley,undefined
来源：
Nature Methods | 2013年 / 10卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A modular optogenetic method for higher-order protein oligomerization uses a single cryptochrome 2-based fusion for rapid, reversible and tunable oligomerization in response to blue light. Inducible aggregation can be used to specifically activate different signaling pathways.
引用
收藏
页码：249 / 252
页数：3
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