Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets

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作者
Liang Wang
Wen-Tao Hou
Jie Wang
Da Xu
Cong Guo
Linfeng Sun
Ke Ruan
Cong-Zhao Zhou
Yuxing Chen
机构
[1] University of Science and Technology of China,The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine
[2] University of Science and Technology of China,School of Life Sciences, Division of Life Sciences and Medicine
来源
Cell Research | 2022年 / 32卷
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页码:501 / 504
页数:3
相关论文
共 2 条
  • [1] Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets
    Wang, Liang
    Hou, Wen-Tao
    Wang, Jie
    Xu, Da
    Guo, Cong
    Sun, Linfeng
    Ruan, Ke
    Zhou, Cong-Zhao
    Chen, Yuxing
    CELL RESEARCH, 2022, 32 (05) : 501 - 504
  • [2] Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin
    Hirano, M
    Maeda, K
    Hayashi, H
    Kusuhara, H
    Sugiyama, Y
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 314 (02): : 876 - 882