Enhancing Detection Sensitivity in Capillary Electrophoresis

被引:0
作者
L. M. Mosulishvili
V. A. Barnov
N. Ya. Tsibakhashvili
H. Engelhardt
W. Beck
机构
[1] Academy of Sciences of Georgia,Andronikashvili Institute of Physics
[2] University of Saarland,undefined
来源
Journal of Analytical Chemistry | 2001年 / 56卷
关键词
Analytical Chemistry; Electrophoresis; Capillary Electrophoresis; Detection Sensitivity; Simple Technique;
D O I
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中图分类号
学科分类号
摘要
A simple technique was proposed for improving detection sensitivity in capillary electrophoresis by the chemical etching of the interior surface of a fused-silica capillary in the detection region. This technique was applied to the electrophoresis of proteins. The sensitivity was found to increase, on the average, by a factor of 4 to 5 after etching a 75-μm i.d. capillary with an HF solution for 7 min.
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页码:512 / 514
页数:2
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