A functional genetic variation of the 5-HT2a receptor affects human memory

被引：0
作者：
Dominique J-F de Quervain
Katharina Henke
Amanda Aerni
Daniel Coluccia
M Axel Wollmer
Christoph Hock
Roger M Nitsch
Andreas Papassotiropoulos
机构：
[1] University of Zürich,Division of Psychiatry Research
来源：
Nature Neuroscience | 2003年 / 6卷
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学科分类号：
摘要：
Human memory capacity is highly variable across individuals and is influenced by both genetic and environmental factors. A roughly 50% heritability estimate1 indicates that naturally occurring genetic variations have an important impact on this cognitive ability. Therefore, we investigated a functional variation of a memory-related serotonin receptor in 349 healthy young volunteers, and found 21% poorer memory performance in subjects with the rare variant.
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页码：1141 / 1142
页数：1
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